Endocrine Abstracts

Aim: Radioiodine activities for the treatment of Graves’ disease hyperthyroidism are still subject to discussion, as is the use of a fixed approach over a dosimetric one. We aimed to evaluate our success rate using a personalized dosimetric approach: instead of the “(MBq I-131×g gland mass×100)/(percentage uptake at 24 h)” activity calculation, we further adjusted for factors such as gender, age, diagnosis, 2 h and 4 h radioiodine uptake, previous medi...

Introduction: The stromal luteoma of the ovary is a rare tumour occurring mostly in post menopausal women. Endocrine symptoms and sometimes virilizing signs may be observed, although abnormal vaginal bleeding is the most frequent manifestation. This tumour is surrounded by ovarian stroma being entirely composed of luteinized cells devoid of crystals of Reinke. Hyperthecosis of ovarian stroma is often observed. Its evolution is always benign.Case report: ...

Introduction: Adrenal tumors are usually detected due to clinical manifestations of hormonal hypersecretion or incidental findings on imaging evaluation. Although most incidentalomas are non-functioning adenomas, it is important to appropriately evaluate such masses to exclude hormonal excess or malignancy.Case description: An 81-year old male was admitted to our hospital for fever with 15 days of evolution. The patient also presented chills and loss of ...

Introduction: Adrenocortical carcinoma (ACC) is a rare and aggressive endocrine malignancy with a poor prognosis. Hormone-secreting ACC appear with manifestations of virilization, feminization or Cushing syndrome.Case Report: A 63-year-old woman with no pathological history of relief was referred to Endocrinology evaluation with an history of deepening of the voice since 1-year ago, as well as hair loss and facial and abdominal hirsutism with 6-month evo...

Background: Residual C-peptide (CP) secretion has been associated with better glycemic control in patients with type 1 diabetes (T1D).Aim: To evaluate how residual fasting CP (fCP) secretion impacts glycemic control in T1D and to identify possible confounding factors.Methods: A retrospective analysis of adult patients with T1D followed in our department that had their fCP and glucose levels obtained on the same blood sample during ...

Background: The use of Flash Glucose Monitoring (FGM) for the management of type 1 diabetes mellitus (T1D) is rapidly increasing.Aims: To assess the longitudinal evolution of glycated haemoglobin (HbA1c) and body mass index (BMI) with the use of FGM in patients with T1D; to determine predictive factors of benefit with the use of this technology.Materials and methods: Retrospective study of T1D patients, using FGM ≥6 months an...

Introduction: Leydig stromal cell tumors are a subtype of steroid tumors that make up to less than 0.1% of the ovarian tumors. These neoplasms can affect women from all ages but are more frequent after menopause, being usually unilateral, benign and small sized. In around 75% of cases, these tumors produce androgenic hormones, causing oligomenorrhea and virilization.Case report: A 39-year-old woman, nulligravid, with complains regarding androgenic alopec...

The relationship between periodontitis and diabetes mellitus (DM) is widely accepted. Several studies identified a greater incidence of periodontitis and an increase of its severity in diabetic patients, approximately threefold.In this study, we want to investigate the influence of type 2 DM (T2DM) in the development of periodontitis.Single center, randomized trial with 90 patients T2DM. Exclusion criteria: chronic renal disease (G...